LaCáN
Mathematical and Computational Modeling
Mechanics plays a prominent role in fundamental biological processes at the level of individual cells and of groups of cells forming tissues. Examples include cell division, the development of embryos, the ability of adult tissues to resist stress and self-repair, or cell migration during cancer invasion. In recent years, a wealth of quantitative experiments have demonstrated a tight interaction between mechanics and biological regulation. These observations also suggest that despite the daunting molecular and structural complexity of cells and tissues, there are simple underlying principles that govern their behaviour. Our goal is to use theoretical modelling and computer simulations to identify such principles. Besides recapitulating specific observations in developing embryos or in-vitro controlled systems, we aim at developing theories and simulations, which will allow us to predict and rationally manipulate living matter.
